My PhD research project was in Comparative Genomics with a focus was evolutionary genomics and the ellucidation of ancient evoltionary traits within genomes. I was part of the CATH structural classification group in the BSM lab at UCL.

Previously I have worked at the Genome Centre at Barts and the London Medical schoolas a bioinformatician. Most of the bioinformatics work there was service and support work for a range of wet labs from within QMUL. After that I worked srcuk on the tomato genome sequencing project. I was responsible implementaing high throughput annotation services the annotation and curation of tomato proteins in UK tomato sequencing effort..

Currently I work for The UCL bioinformatics Group developing GenTHREADER and maintaining our web services.

Lise S, Buchan DW, Pontil M, Jones DT
Predictions of hot spot residues at protein-protein interfaces using support vector machines.
PLoS One. 2011 e16774

Buchan DW, Ward SM, Lobley AE, Nugent TC, Bryson K,Jones DT
Protein annotation and modelling servers at University College London.
Nucl. Acids Res. 2010 38 Suppl, W563-W568

The Tomato Genome Sequencing Consortium
A Snapshot of the Emerging Tomato Genome Sequence
The Plant Genome 2009 2 78-92

Ranea JAG, Buchan DWA, Thornton JM, Orengo CA
Evolution of Protein Superfamilies and Bacterial Genome Size
Jol Mol Bio 2004 Feb;336(4) 871-887.

Lee D, Grant A, Buchan D, Orengo C.
A structural perspective on genome evolution.
Curr Opin Struct Biol. 2003 Jun;13(3):359-69.

Buchan DW, Rison SC, Bray J E, Pearl F, Lee D, Thornton J M, Orengo C A
Gene3D: Structural Assignment for the Biologist and Bioinformatacist Alike.
Nucleic Acids Res. 2003 Jan 1;31(1):469-473.

Buchan DW, Shepherd AJ, Lee D, Pearl FM, Rison SC, Thornton JM, Orengo CA.
Gene3D: Structural Assignment for Whole Genes and Genomes Using the CATH Domain Structure Database.
Genome Res. 2002 Mar;12(3):503-14.

Pearl FM, Lee D, Bray JE, Buchan DW, Shepherd AJ, Orengo CA.
The CATH extended protein-family database: Providing structural annotations for genome sequences.
Protein Sci. 2002 Feb;11(2):233-44.

Orengo CA, Bray JE, Buchan DW, Harrison A, Lee D, Pearl FM, Sillitoe I, Todd AE, Thornton JM.
The CATH protein family database: A resource for structural and functional annotation of genomes.
Proteomics. 2002 Jan;2(1):11-21.

Pearl FM, Martin N, Bray JE, Buchan DW, Harrison AP, Lee D, Reeves GA, Shepherd AJ, Sillitoe I, Todd AE, Thornton JM, Orengo CA.
A rapid classification protocol for the CATH Domain Database to support structural genomics.
Nucleic Acids Res. 2001 Jan 1;29(1):223-7.

Jitsu

I'm a member of UCLU Jitsu club, which I joined in October 2000. It's a great laugh, the people are nice and there is a good social side to the club (plug, plug, plug). As a martial art it belongs to the same group as Judo and Shorinji Kempo and involves throwing and grappling techniques, our style is very self defense orientated. If you want to know more you can check out their marvellous web site by going to www.jitsu.uclu.org

Music

I like music and in a futile attempt to seem cool I also DJ and have and overly large music collection. Previously I have DJ'd in clubs across london from the 414 to and Cargo, before then I helped organise a range of free/illegal parties for sounds systems like 'Smiling Fish Psychedelic Discotheque' and Channel23 (among others). Today it's more of a hobby but you can hear some of my current mixes at my soundcloud page and my Let's Mix page

Games

Ah yes, the evil lure of the computer game. Well, it all started in 1982 (or was it 1983?) and since then I've played more games than I care to remember. I'm rather good (even if I do say so myself) and I like a well made game. Anyway, I like interesting games, something with a bit of originality and with a bit of thought/elegance in the implementation. Difficult games are also highly welcome (but not unplayable games). I have a review/blog at Itchy Thumbs

Cooking

I like good food and I'm damn good at cooking. I know you're all dying to get your hands on these Recipes

I can do all manner of web site malarkey (Ok, HTML, PERL CGI and a tiny bit of javascript really) and have written and maintain the following sites. I like sites to be fairly straight forward and not too over designed. I can't believe how many truely awful sites are out there, has nobody heard of page setting? Has the last 100 years of magazine page design passed everyone on the planet by? Eh?, Eh? Answer me that.

Bioinformatics Links

The UCL Bioinformatics Group - Where I work
The CATH database - Database of protein structural domains
Gene3D - Database of genome structural annotations
The NCBI - Genbank et al
PubMed, at the NCBI - Journal engine.
Others Links

The Onion - Spoof news
GameFAQS - Computer Game hints and solutions

Dr Daniel Buchan

Dept. of Computer Science,
University College London,
Gower Street, London,
WC1E 6BT, United Kingdom.
Tel:+44 (0)20 7679 3718
Email: d.buchan@cs.ucl.ac.uk